![]() Serum and perilymphatic fluid samples were analyzed using mass spectrophotometry to detect AVN-C. Wild-type C57BL/6 mice were used to generate several HL models. In this study, we investigated whether AVN-C can protect auditory hair cells, and preserve hearing from noise trauma and ototoxic drugs. Avenanthramide (AVN), a natural product extracted from oats, has been reported to possess anti-oxidant/inflammatory properties, and protect several types of cells. While the incidence of HL is growing continuously, there are, so far, no adequate drugs to prevent or treat HL. Noise exposure or ototoxic drugs instigate various types of damage to the cochlea, resulting in hearing loss (HL).
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